XMD8-92 mterene with animals in the 100

with animals in the 100 mg/kg dose group showing levels comparable with those of disease-free control animals

Ca/c2*1-3-5-11(24)22-16-13-17(20-8-19-16)23(9-21-13)18-15(30-12(25)6-4-2)14-10(29-18)7-28-32(26

KRCA-0008 is a potent dual inhibitor of Ack1 and anaplastic lymphoma kinase (ALK)

O=C1CN2[C@@H]3CC1C[C@H]2CC(C3)OC(=O)C1=CNC2=CC=CC=C12

XMD8-92 mterene with animals in the 100XMD8 92 is an ERK5 BMK1 inhibitor and also BRD4 inhibitor. XMD8 92 inhibits pancreatic tumor xenograft growth via a DCLK1 dependent mechanism. XMD8 92 blocks cellular BMK1 activation and significantly suppresses tumor growth in lung and cervical tumor models and is well tolerated in animals. Product information CAS Number: 1234480 50 2 Molecular Weight: 474. 55 Formula: C26H30N6O3 Chemical Name: 5 {[2 ethoxy 4 (4 hydroxypiperidin 1 yl)phenyl]amino}